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KMID : 0869020100130010043
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Journal of Korean Orthopaedic Research Society
2010 Volume.13 No. 1 p.43 ~ p.51
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Role of Mesenchymal Stem Cells in Patients with Nontraumatic Osteonecrosis of the Femoral Head
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Song Min-Jung
Bae Jung-Yun
Cho Hyung-Joon
Suh Kuen-Tak
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Abstract
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Mesenchymal stem cells are stem cells originated from the mesoderm have the capacity to differentiate into cells of connective tissue lineages, including bone, fat, cartilage and muscle. Nontraumatic osteonecrosis of the femoral head has been suggested the cause is likely relevant to the poor proliferation activity of mesenchymal stem cells in the femoral head region. The altered function of mesenchymal stem cells may be responsible for the pathogenesis and progression of osteonecrosis, in steroid or alcohol induced nontraumatic osteonecrosis of femoral head.
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KEYWORD
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Mesenchymal stem cells, Nontraumatic osteonecrosis, Femoral head
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